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Jumat, 04 Februari 2011

Prostate Cancer

Prostate Cancer is a malignant tumor that grows in the prostate gland.

Prostate Cancer, Prostate cancer is very common.
Microscopic examination of prostate tissue after surgery and at autopsy showed cancer in 50% of men aged over 70 years and in all men aged over 90 years.

Most cancers do not cause symptoms because of its spread is very slow.

The cause is unknown, although several studies have shown a link between a diet high in fat and elevated levels of testosterone.

Prostate cancer is the leading cause of cancer deaths in men and no 3 is the main cause kematin from cancer in men over 74 years.
Prostate cancer is rarely found in men aged less than 40 years.

Men who have a higher risk for prostate cancer is a black man aged over 60 years, farmer, painter and cadmium exposure.
The lowest incidence was found in Japanese men and vegetarians.

Prostate cancer is grouped into
Stage A: lump / tumor can not be palpable on physical examination, usually discovered by accident after prostate surgery for other diseases.

Stage B: tumor confined to the prostate and usually found on physical examination or PSA test.

Stage C: tumor has spread outside the prostate capsule, but not yet spread to lymph nodes.

Stage D: Cancer has spread (metastasis) to the regional lymph nodes or other body parts (eg bones and lungs).

What are the symptoms of prostate cancer?
Prostate cancer usually develops slowly and does not cause symptoms until the cancer has reached an advanced stage.

Sometimes the symptoms resemble BPH, namely in the form of difficulty in urination and frequent urination.

Symptoms are due to cancer causing partial blockage of urine flow through the urethra.

Prostate cancer can cause red urine (because it contains blood) or urine caused the sudden arrest.

In some cases, newly diagnosed prostate cancer after spread to the bone (especially the pelvic bones, ribs and spine) or to the kidneys (causing kidney failure.)
Painful bone cancer and brittle bones become so susceptible to fractures (broken bones).

After the cancer spreads, usually the patient will suffer from anemia.

Prostate cancer can also spread to the brain and cause seizures and mental or other neurological symptoms.

Other symptoms are:
Usually the urine still dripping
Pain when urinating
Pain when ejaculating
Lower back pain
Pain when defecating
Nocturia (urination at night)
Incontinence uri (beser)
Bone pain or bone pain when pressed
Hematuria (blood in urine)
Abdominal pain
Weight loss.

How do I diagnose prostate cancer?
The best way to screen for prostate cancer is to perform digital rectal examination and blood tests.

Digital rectal prostate cancer patients will show the existence of hard lumps of irregular shape.

On examination the blood was measured levels of prostate specific antigen (PSA), which is usually elevated in patients with prostate cancer, but also can increase (not too high) in patients with BPH.

If the digital rectal examination found a lump, then conducted an ultrasound examination.
By doing Skening X-rays or bone, can be known of the spread of cancer to bone.

Other tests are usually done:
Analysis of the urine
Cytology of urine or prostatic fluid
Prostate biopsy.

How does prostate cancer treatment?
Appropriate treatment for prostate cancer is still debated.
Treatment options vary, depending on the stage:

In the early stages can be used prostatectomy (removal of prostate) and radiation therapy.

If the cancer has spread, it could be hormonal manipulation (to reduce testosterone levels through medication or removal of the testes) or chemotherapy.


Drugs that can be used to treat prostate cancer are:
- Mitoxantron
- Prednisone
- Paclitaxel
- Dosetaxel
- Estramustin
- Adriamycin.
The side effects vary and depend on the drugs given.

Monitoring needs to be done for prostate cancer
Whatever type of treatment he underwent, the patient will be monitored closely on the development of the disease.
Monitoring include:
Blood tests to determine PSA levels (usually every 3 months - 1 year).

Skening and / or CT scan to determine the spread of bone cancer.

Complete blood count to monitor the signs and symptoms of anemia.

Monitoring for signs and other symptoms indicating disease progression (such as fatigue, weight loss, more severe pain, decreased bowel and bladder function, and weakness).

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